Sleep Balance Profile w/Diurnal Norepinephrine & Epinephrine Add On– Evaluation of Melatonin and Cortisol Rhythm for Restorative Sleep

The Sleep Balance Profile from ZRT Laboratory provides a detailed evaluation of the hormones that regulate your sleep–wake cycle, helping identify imbalances that contribute to insomnia, fatigue, mood changes, and metabolic issues.

Sleep disturbances affect more than 60 million Americans, impacting cognitive performance, mood, metabolism, and cardiovascular health. Chronic sleep loss—defined as sleeping six hours or less per night—has been linked to depression, obesity, diabetes, and heart disease.

Our bodies follow a natural circadian rhythm, guided by the balance of cortisol and melatonin. Cortisol rises in the morning to energize the body, while melatonin increases at night to promote deep, restorative sleep. Disruptions in this rhythm—caused by stress, shift work, blue light exposure, hormonal imbalance, or blood sugar fluctuations—can lead to poor sleep quality and daytime exhaustion.

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What This Test Measures

The ZRT Sleep Balance Profile measures the urinary metabolite of melatonin, 6-sulfatoxymelatonin (MT6s), along with cortisol and cortisone at four specific times during the day and night. These results provide insight into whether high nighttime cortisol, low melatonin, or adrenal imbalance is contributing to sleep disruption.

Understanding this relationship allows practitioners to recommend targeted lifestyle, nutritional, and hormonal interventions to restore balance and improve sleep quality.

Useful For Individuals Experiencing:

• Insomnia or difficulty staying asleep

• Daytime fatigue or low energy

• Mood disorders, depression, or anxiety

• Weight gain or sugar cravings

• Sleep apnea or restless sleep

• Hormone or adrenal imbalances

• Cardiovascular disease, diabetes, or hypertension

WHY CHOOSE THIS TEST

The Sleep Balance Profile provides a powerful look at how your body’s hormonal rhythm affects your ability to rest and recover. By pinpointing whether stress, hormone imbalance, or environmental factors are driving poor sleep, this test helps guide effective, natural solutions for long-term restorative rest.

TEST REQUIREMENTS

Four timed urine collections – first morning, second morning, evening, and nighttime – are dried onto paper cards using the convenient at-home kit. Samples are stable for shipping and require no refrigeration.

INCLUDES

✅ Sleep Balance Profile (UDH III) w/Diurnal Norepinephrine & Epinephrine Add On (Dried Urine Test)
✅ Doctor’s Review and Interpretation of Results
✅ Personalized Recommendations to Improve Sleep and Hormone Balance

✅ Free Shipping in the Lower 48 US States

Important: This test is not available to residents of New York State. Orders or samples originating from New York will be canceled, and any specimens received will be discarded.